How a stroke causes bladder problems

Stroke can cause a range of bladder problems. This occurs due to the disruption to the brain-bladder communication channels. This post explores how it happens.

Another post explores what bladder problems stroke can cause.

Table of contents

  1. The bladder control mechanism
  2. The role of the two gates in the incontinence
  3. How the brain communicates with the bladder in bladder control
  4. How stroke can disrupt brain-bladder communication

1. The bladder control mechanism

Figure 1 depicts the inside of a bladder. The tubes (ureters) transport urine from our kidneys to the bladder. The bladder can store about 450-500ml of urine. Its wall consists of a strong muscle layer, called “detrusor muscle”. This muscle contracts to squeeze out urine when the specialized brain areas send messages to do so. However, the brain should receive information from the stretching bladder wall about the increase in urine volume. This happens through a web of nerve endings that populate the outer layer of the bladder wall. The message goes up to a place at the lower part of the brain stem.

This image has an empty alt attribute; its file name is 2605_The_Bladder.jpg
Figure 1:
A cross-section of the bladder. Source: Wikimedia Commons. illustration from the Illustration from Anatomy & Physiology, Connexions Web site, licensed under CC BY 3.0

2. The role of the two gates in the incontinence

Go through Figure 2. Find out the two control gates; these are named “sphincters” because they act like valves.

  • The inner gate (named inner urethral sphincter)
  • The outer gate (named outer (external) urethral sphincter).
Figure 2:
Bladder gates (changes made by strokecarer.com). Source: Wikimedia Commons. illustration from the Illustration from Anatomy & Physiology, Connexions Web site, licensed under CC BY 3.0

We can find these gates near the tapering lower end of the bladder. As soon as the transit center at the spinal cord receives approval from the brain, it messages the gates open, and the bladder wall contract. As a result, urine will flow out.

3. How the brain communicates with the bladder to avoid incontinence problems

The brain owns a widespread network covering every minute area of our body as shown in Figure 3. Obviously, it also includes the bladder and bladder gates.

Figure 3:
Brain’s nerve communication network;
image source: openstax.org under the license of CC BY 4.0.

4. Brain areas that prevent incontinence problems

When the bladder wall muscle – detrusor – stretches with urine, the nerve network that covers its wall messages the center at the Pons (Figure 4) via the spinal cord. This center, named “Pontine micturition center”, seeks permission from its higher centers to activate the peeing reflex which it normally does. Under normal situations, the higher centers veto the Pons’ center’s request until a suitable time and place find to pee. In this way, the higher centers suppress this urgent message to contract from the bladder wall and to relax the internal gate.

In contrast, the other route transports messages to inhibit the wall contraction and close valves.

Stroke can disrupt brain-bladder communication causing continence problems.

Stroke kills neurons in areas where blood supply is stopped. It happens either due to a blockage to the supply or rupture of a carrying vessel. The former is called “ischemic stroke” and the latter is called “hemorrhagic stroke”. These stroke types are discussed in this post. When the disruption to the blood supply occurs to the areas that are responsible for peeing, peeing problems result. The next post discusses what types of bladder problems stroke can result in.

Author: Prasantha De Silva

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